Twabbis,
Do your own research, I don't know where some people pull their ballistics from, but I think its thin air. In particular when they try to correlate ballistics to killing animals. Ballistics are fun to talk about, but the reality is, they don't mean much of jack chit when it comes to how a given caliber will perform on game.
Case in point is the bullchit about 1200 foot lbs being the minimum to kill elk...pure hogwash. Bullets kill by doing internal damage causing blood loss and associated drop in blood pressure. Of course, central nervous system damage to the spine or brain will also kill an animal or incapacitate them allowing for a follow up shot.
Further, the information provided to you about your 25/06 and 110 accubonds is a joke. I would reckon that the dud that posted that assumed a MV of 3K or less. If you aren't pushing a 110 at 3100+, you're leaving performance on the table. Assuming 3100, you would actually have over 1,000 ft/lbs at 500...more than enough to kill an elk, bear, deer, etc. All that's needed is enough energy to allow the bullet to reach vital organs and expand the bullet.
I also really enjoy a good chuckle, from those giving advice, that you better make sure the animal is broadside and you're only taking a good shot at extended range (thanks for that captain obvious). As if to say, its OK to take a bad shot with something bigger. A bad shot is a bad shot, doesn't make a chittin' bit of difference what weapon you're using. Bullet placement matters most...period.
Allow me to burst a few bubbles and myths...
Cow elk, 7-08, 140 AB, MV 2850 629 yards took a half dozen staggering steps, dead in seconds. Bullet exited on a slight quartering away shot.
Same rifle, load, yada yada...486 yards again slightly quartering away. Recovered the bullet on the off-side, just under the hide of a broken shoulder (you can see the blood from the entrance side just in front of mid-body):
Recovered 140 AB from that bull:
Finally, if you shoot your 25/06 well out to 500, use it and make sure you have a good pack, knife, wrapping paper, and freezer space...you'll need all those things.