Every rifle has a personality of it's own but here's my experience with then in two 280AI's and a 7mm mag (yes, different calibers than yours).
They don't shoot accurately enough for me and no where near to the potential of the rifles. I used 2-3 different powders and seating depths but nothing seemed to work right for me, my son or my brother. We sold our substantial remaining stock of them.
Some guys have had wonderful luck with them in their rifles of various cartridges and calibers but the 3 rifles we used didn't like them...so, you should try them and experiment a bit and see how they work for you and report back.
Zeke