I've never had elk and deer hunters impact my pronghorn hunts.What others said find and shoot it first day in the morning or start middle of week after opening weekend there- nearly half the pronghorn shot get killed the first two days I would guess. Just do it before deer and elk get started for a quality experience. I hunted this year on a weekday opener Sept 15th and just the drop off from first day to second was big.
We focus on trophy elk, mule deer, antelope and moose hunts and take B&C bucks most years.