I don't know about in the 30.06, but the only deer out of about 30 that I've killed with a muzzy, was lost with a SST.
Giant whitetail, 150 yards out, shoulder shot, massive blood and hair, tracked him to a pool of blood and then he crossed a 800 yard picked field. My guess is that the bulled fragmented badly and didn't achieve more than shallow penetration.
That was the year I ran out of my barnes 290's and decided to try something else. Bummer, as it's the best deer I've had in front of a barrel too.