Out of the box and brand new, they likely need to be programmed as it has no buttons or menus. You will need an interface cable and software. Some radios will only work with OEM cables, others aren't so finicky and will communicate through a generic cable.
As far as software, I've had minimal issues programming various radios using CHIRP (freeware).
To be safe, you want analog (they can be upgraded to digital later). Most Digital (DMR) configurations require a software and yet another license plus a digital repeater.