First answer these questions.
#1-If your rifle is sighted-in to be dead-on at 125 yards, where will your bullet strike at 200 yards?
#2-If you sight-in dead-on at 200 yards, where will your bullet strike if you are presented with a 100 yard shot?
#3-Will you know that the animal is exactly 200 yards?
#4-If not, do you know how much adding or subtracting 25 yards of range will effect the impact point of your bullet?
#5-Do you know what the shooting angle and wind speed will do to the bullet?
#6-Is your 7" group shot off a bench, or after you've got your blood pumping by climbing hills, and taking into consideration that you may be a little excited because you are now considering shooting at game instead of a target?
How you answered those questions, should give you the answer to your question.
You see, there are many variables. Lets assume we are talking about deer.
With your stated load:
If you sight your gun in to be dead-on at 125 yards, you are very close to being sighted-in at maximum point blank range. That is to say; muzzle to 150 yards, the bullet will not be above or below line of sight by more than 3". I know, the vitals are 8"+ on a big buck, but I'm being conservative here, using 6" as an example to take-up some of the slack in all the variables. Adding 50 more yards, extending your range to 200 yards, your bullet will hit nearly 14" low! Can anybody be sure of the exact range, the exact bullet drop, the exact wind speed, range, etc. etc. etc.? Can we estimate all of these variables in a matter of seconds and consistantly place the bullet in the vital zone, or just occasionally get lucky and pull off a "Hail Mary"? We can go on forever with this debate, and I see I'm going against the flow here, but in my opinion, if we are talking about deer, 200 yard shots at game with your load is NOT ethical.