Yes, but only a start. Don't discount any combination until you have tried it in your gun. I started out with the old TC and some guns would shoot great and some would not - - and some - - - - well you just had to find the right combination for them to shoot accurately at all. Some you would have to shoot the barrels in before they would group (several hundred shots).
I'm just here to tell you that stories could get wild about the slow twist days and combination used. Heard of one person using a little modern powder along with black powder. Ended up with his head stitched up and a blown barrel.
Most of you modern ML hunters it is just another hunt, but in the "beginin" it was a way of life.