I bought a small business in IF in 2006, but I live about 45 minutes to the east in Swan Valley. Just to couch my perspective, I'm from the east coast but lived in northeast UT for several years in the 80s and have hunted and fished out here off and on since then, and finally moved back in 2004 to Teton Valley, and then to Swan Valley. Honestly, I think many women who didn't grow up here, or who grew up in warmer places, won't like it. Winters are long, but if your wife likes winter sports then that is a positive. Also, I don't know if you are LDS or not, but I'm sure you know that that culture is the majority here. I'm not LDS but I certainly get along well with them and most of my co-workers are, but people from different cultures often are bothered by it, more so with women. Don't jump on me folks, that's just one outsider's experience and observations.
As far as the hunting goes, if you are a trophy hunter, in my opinion one would be better off for deer being a resident in WY or CO, or for elk being a resident in WY or MT or one of the southwest states, but Idaho is a great opportunity state and seasons are long and there is great diversity, which is nice. If you hunt hard you should have a full freezer every year. Genetically ID has tremendous mule deer potential but the state isn't managed for trophy deer, and there are simply too many of us now, with all our high tech equipment, on top of the other challenges facing mule deer these days which are many. As a resident it isn't too hard to draw a moose tag, and within a few years of becoming a resident I had my moose and a bighorn ram, however, draw odds on the quality hunts for all species are trending downward each year, though that's true west wide, supply and demand.
Trout fishing wise this is a excellent place to be, as has been noted, with lots of good water nearby. You are also within a few hours of steelhead fishing on the Salmon.
Lastly, the economy in the IF area is taking some blows from the waves of layoffs happening at the INL. If the INL can morph into an entity that is again capable of sucking huge quantities of federal dollars, then IF will continue to grow, but if it languishes IF's economy will too. If the INL were to die completely (not likely), all the area would have as an economic driver is Ag. In general Idaho is a poor state and we are last or near last in a lot of categories when compared nationally. I know of a number of instances where outsiders who had school aged kids were offered good jobs here, but turned them down after they evaluated the school situation. Just the facts as I see them; I hope I'm not offending natives. I really like being here, and not sure I could be happy anywhere else but the northern rocky mountain region. If you can afford non-res licenses you are close to WY and MT and can hunt 3 states every year.