Obviously if you apply for 1 in 100 draw odd units the draw stats indicate you have a poor chance to draw in your lifetime. Each unit is likely different and can change somewhat from 1 year to the next. Almost across the board, the demand for high demand limited tags is increasing and draw odds are decreasing each and every year for nonres DIY/OYO hunters!
Another consideration is you never know what may happen 5 to 10 years from now in Wyo. Using the Big 5 species as a great example. Draw odds were cut in 1/2 for all nonres since 1/2 the tags quotas were suddenly changed. In the same case, Wyo res draw odds improved a fraction of a fraction of a %!
Something that can dramatically change draw odds is winterkill, fawn crop, disease, predators, etc. In years where there are high numbers of critters there generally are more tags issued. You may notice Wyo deer and antelope numbers are struggling across Wyo so there generally are fewer tags issued than a few years ago.
In any given year nonres are issued only a few tags. Landowner tags are filtered off the top of the nonres quotas and landowner tags are currently unlimited to those that qualify. This may leave few to 0 tags issued to nonres in the draw....especially in high demand elk units with private land.
There's a lot of considerations when deciding if it's worth building and buying preference pts or applying for slim draw odd units. Obviously each state is a little different and may offer different options. One thing for certain, it isn't getting any easier to draw high demand, limited tags!