Welllllll, basically The conical will blow a hole through anything on this continent. On some of those animals you MAY, ALMOST be able to see through them. They have a reputation from depositing extreme energy onto the poor critters on the sending and the receiving end of the gun. If I was after a BIG BULL, in the rut, this would be my choice.
They have a rainbow trajectory, after about 125 yaards they are dropping like a rock.
A sabot is the ballistic equivelent of a .44 mag rifle. The .44 grain bullet has the same energy as a .44 Mag pistol at the barrel, after the ML sabot bullet has traveled 100 yards or so, so it still has plenty of energy for elk and it will shoot real flat, to farther than iron sights should be used (200 yards or so) (look at .44 mag rifle ballistics on the Remington website) and it does kick ALOT less. I agree, use the heavier bullet.
I have not found that they take an excessive amount of time to load...They can be hard to load, but I takes a long time to load a conical anyways and if you miss, whatever it is is going to bound away or watch you reload, I don't see 10-20 seconds longer (than normal) really mattering.
Don't overlook a roundball on critters. On my 3/8" thick steel plates they leave a NASTY crater. They have a rep for excellent energy transfer and bullet becomes a pancake after hitting. I've heard several people say that deer just fall over dead (and if I remember right, they find the ball against the far side's hide). They have about the same ballistics as a conical (rainbow) and kick about like a sabot and at about 75 yards or so are shedding fps like water on a duck and after that, they don't hit all that hard. They are very adequete closer than that, on critters upto a cow elk (or so I've heard, Myself, I wouldn't test the theory past 50 yards or so) and they'll knock deer down out to about 125 yards or so...don't be surprised if somebody responds and says that they've used a ball, on bulls at 100 yards or more, w/good results.
My last cow hunt was in AZ and I used a 255 lead SWC .429 (I cast em and I like lead bullets). I now live in CO, where sabots are verboten and I use the RBs on deer (and maybe cows, depending on the distance I expect) and a conical on bulls. I'd probably use a roundball and a sabot interchangably, if I had the choice, depending on the range.