Piper, most of the loads that i develop, not all that many, i do so in the Summer. Personally, i want the most that i can get from my cartridge so i want them on the hot side. If they shoot thru my rifles during the summer when it's warm out, and still don't show signs of too much pressure, i feel safe hunting with them later on when it's cooler...buck season.
If a guy does the opposite, develope a loading when it's cold and shooting them when it's warm...bad things can and do happen.
Don't know about Reloader22 in particular, i just use this caution in all my loadings with all the powders that i use.
Joey